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PPAVISC PFS 2.4 (Hydroxypropyl Methyl Cellulose Ophthalmic Solution USP) is sterile, apyrogen free clear & transparent viscous solution of highly purified HPMC. The chemical name of active ingredient is Cellulose 2-hydroxypropylmethyl ether. Each mL contains: Hydroxypropyl Methylcellulose USP 2.4%w/v & Sterile isotonic base q.s. Appavisc PFS 2.4 solution is formulated to a viscosity of NLT 7000 cps.
HPMC consists of large macromolecules that exert a protective effect on ocular tissue during surgical procedures. It limits the mechanical damage from invasive procedures by separating and lubricating tissues .The HPMC also shows to decrease corneal endothelial cell loss during surgery. It is routinely used as an adjuvantin cataract surgery, IOL, corneal transplantation and surgery of glaucoma, etc. HPMC goes well with the lens and other corneal surfaces because of its low contact angle.
Appavisc PFS 2.4 is indicated as a surgical aid (medical device) during surgical procedures involving the anterior chamber of the eye, including extraction of the lens and insertion of intraocular lenses. It maintains the depth of the anterior chamber during the whole surgical procedure and permits greater operative precision without the risk of damaging the endothelium of the cornea or other intraocular tissues.